Sequence dependent conformational variations of collagen triple-helical structure

Nat Struct Biol. 1999 May;6(5):454-7. doi: 10.1038/8259.

Abstract

The 2 A crystal structure reported here of the collagen-like model peptide, T3-785, provides the first visualization of how the sequence of collagen defines distinctive local conformational variations in triple-helical structure.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Amino Acid Sequence
  • Collagen / chemistry*
  • Collagen / metabolism
  • Crystallization
  • Crystallography, X-Ray
  • Humans
  • Hydrogen Bonding
  • Models, Molecular
  • Molecular Sequence Data
  • Peptide Fragments / chemistry*
  • Peptide Fragments / metabolism
  • Protein Conformation
  • Protein Structure, Secondary
  • Sequence Alignment
  • Water / chemistry
  • Water / metabolism

Substances

  • Peptide Fragments
  • T3-785 peptide
  • Water
  • Collagen

Associated data

  • PDB/1BKV
  • PDB/R1BKVSF