Resistance gene capture

Curr Opin Microbiol. 1999 Oct;2(5):483-8. doi: 10.1016/s1369-5274(99)00004-1.

Abstract

Integrons are the primary mechanism for antibiotic-resistance gene capture and dissemination among Gram-negative bacteria. The recent finding of super-integron structures in the genomes of several bacterial species has expanded their role in genome evolution and suggests that they are the source of mobile multi-resistant integrons.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Anti-Bacterial Agents / pharmacology*
  • Bacteria / drug effects*
  • Bacteria / genetics
  • DNA Transposable Elements*
  • Drug Resistance, Microbial / genetics*
  • Genes, Bacterial*
  • Humans

Substances

  • Anti-Bacterial Agents
  • DNA Transposable Elements