Abstract
In a prospective study of the efficacy of the ketogenic diet in children with severe, refractory epilepsy, data were collected on medication changes over 1 year. Cost reductions in medications were calculated over the first year and estimated for a second year. Fifty-seven percent of the children stayed on the diet for 1 year, and 74% of these children had their number of medications reduced. Forty-eight percent of children who stayed on the diet were on no medications at 12 months follow-up. Daily medication costs were reduced by nearly 70%.
Publication types
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Clinical Trial
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Comparative Study
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Research Support, Non-U.S. Gov't
MeSH terms
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Adolescent
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Anticonvulsants / administration & dosage
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Anticonvulsants / economics*
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Anticonvulsants / therapeutic use
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Child
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Child, Preschool
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Cost-Benefit Analysis
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Dietary Fats / administration & dosage*
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Dose-Response Relationship, Drug
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Drug Costs*
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Epilepsy / diet therapy*
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Epilepsy / drug therapy
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Epilepsy / economics*
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Female
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Follow-Up Studies
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Food-Drug Interactions
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Humans
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Infant
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Ketosis* / etiology
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Ketosis* / metabolism
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Male
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Patient Dropouts
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Prospective Studies
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Treatment Outcome
Substances
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Anticonvulsants
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Dietary Fats