Optic neuritis in herpes zoster ophthalmicus

Jpn J Ophthalmol. 2000 Sep-Oct;44(5):550-4. doi: 10.1016/s0021-5155(00)00204-5.

Abstract

Background: Optic neuritis in herpes zoster ophthalmicus (HZO) has been reported rarely. We report two cases of HZO optic neuritis with detailed magnetic resonance imaging study and treatment responses.

Cases: One patient presented with anterior optic nerve involvement, and the second presented with retrobulbar optic neuritis. Contrast enhanced T(1)-weighted images were obtained in these 2 patients. Intravenous acyclovir and oral prednisolone were given simultaneously.

Observations: Magnetic resonance imaging revealed peripheral enhancement of the optic nerve sheath complex on T(1)-weighted scan. Both patients recovered their vision within 3 months following the start of treatment.

Conclusions: Magnetic resonance imaging is helpful for the diagnosis of HZO optic neuritis. Systemic acyclovir and steroid are effective in the treatment of HZO optic neuritis.

Publication types

  • Case Reports

MeSH terms

  • Acyclovir / administration & dosage
  • Aged
  • Antibodies, Viral / analysis
  • Antiviral Agents / administration & dosage
  • Diagnosis, Differential
  • Drug Administration Routes
  • Drug Therapy, Combination
  • Fluorescein Angiography
  • Fundus Oculi
  • Glucocorticoids / administration & dosage
  • Herpes Zoster Ophthalmicus / complications*
  • Herpes Zoster Ophthalmicus / diagnosis
  • Herpes Zoster Ophthalmicus / drug therapy
  • Herpes Zoster Ophthalmicus / virology
  • Herpesvirus 3, Human / immunology
  • Humans
  • Magnetic Resonance Imaging
  • Male
  • Optic Neuritis / diagnosis
  • Optic Neuritis / drug therapy
  • Optic Neuritis / etiology*
  • Optic Neuritis / virology
  • Prednisolone / administration & dosage
  • Prognosis
  • Visual Acuity
  • Visual Fields

Substances

  • Antibodies, Viral
  • Antiviral Agents
  • Glucocorticoids
  • Prednisolone
  • Acyclovir