Re-staging mitosis: a contemporary view of mitotic progression

Nat Cell Biol. 2001 Jan;3(1):E3-6. doi: 10.1038/35050676.

Abstract

The process of cell division, or mitosis, has fascinated biologists since its discovery in the late 1870s. Progress through mitosis is traditionally divided into stages that were defined over 100 years ago from analyses of fixed material from higher plants and animals. However, this terminology often leads to ambiguity, especially when comparing different systems. We therefore suggest that mitosis can be re-staged to reflect more accurately the molecular pathways that underlie key transitions.

Publication types

  • Historical Article
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Animals
  • Biology / history*
  • G2 Phase / physiology
  • History, 19th Century
  • Humans
  • Interphase / physiology
  • Mitosis / physiology*