Abstract
Here we show that the rate of poleward chromosome motion in zw10-null mutants is greatly attenuated throughout the division process, and that chromosome disjunction at anaphase is highly asynchronous. Our results show that ZW10 protein, together with Rod, is involved in production and/or regulation of the force responsible for poleward chromosome motion.
Publication types
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Animals
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Cell Cycle Proteins*
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Chromosomes / physiology*
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Drosophila / cytology
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Drosophila / genetics*
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Drosophila / physiology*
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Drosophila Proteins*
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Genes, Insect
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Insect Proteins / genetics*
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Insect Proteins / physiology*
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Male
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Meiosis / genetics
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Meiosis / physiology
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Microscopy, Video
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Molecular Motor Proteins / genetics
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Molecular Motor Proteins / physiology
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Movement / physiology
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Mutation*
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Spermatocytes / cytology
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Spermatocytes / physiology
Substances
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Cell Cycle Proteins
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Drosophila Proteins
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Insect Proteins
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Molecular Motor Proteins
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Zw10 protein, Drosophila