Idiotypic regulation of anti-factor VIII antibodies

M D Kazatchkine; S Lacroix-Desmazes; A Moreau; S V Kaveri

Idiotypic regulation of anti-factor VIII antibodies

Haematologica. 2000 Oct;85(10 Suppl):97-9.

Authors

M D Kazatchkine¹, S Lacroix-Desmazes, A Moreau, S V Kaveri

Affiliation

¹ INSERM U430 and University Pierre et Marie Curie, H pital Broussais, Paris, France.

PMID: 11187885

Abstract

This review focuses on the relationship between natural autoreactivity, autoimmunity in disease and antigen-driven immune responses to factor VIII and on idiotype-mediated immune regulation of anti-factor VIII antibodies in health and disease.

Publication types

Review

MeSH terms

Antibodies, Anti-Idiotypic / blood
Antibodies, Anti-Idiotypic / immunology*
Autoantibodies / blood
Autoantibodies / immunology
Factor VIII / immunology*
Hemophilia A / immunology
Humans
Immunoglobulin Idiotypes / blood
Isoantibodies / blood
Isoantibodies / immunology

Substances

Antibodies, Anti-Idiotypic
Autoantibodies
Immunoglobulin Idiotypes
Isoantibodies
Factor VIII