Diabetes, impaired fasting glucose, and elevated HbA1c in U.S. adolescents: the Third National Health and Nutrition Examination Survey

Diabetes Care. 2001 May;24(5):834-7. doi: 10.2337/diacare.24.5.834.

Abstract

Objective: Using population-based data, we estimated the prevalence of diabetes, impaired fasting glucose, and elevated HbA1c (>6%) levels in U.S. adolescents.

Research design and methods: The Third National Health and Nutrition Examination Survey (1988-1994) examined a representative sample of the U.S. population, which included 2,867 adolescents aged 12-19 years who had serum glucose measured.

Results: A total of 13 adolescents in the sample were considered to have diabetes; 9 reported using insulin, 2 reported using oral agents only, and 2 did not report any treatment but had high glucose levels (> or = 11.1 mmol/l regardless of length of fast or > or = 7.0 mmol/l after an 8-h fast). Four of these cases (31% of the sample with diabetes) were considered to have type 2 diabetes. The estimated prevalence of diabetes (all types) per 100 adolescents ages 12-19 years was 0.41% (95% confidence interval 0-0.86). The prevalence of impaired fasting glucose (> or = 6.1 mmol/l) among adolescents without diabetes who had fasted for at least 8 h was 1.76% (0.02-3.50). The prevalence of elevated HbA1c (>6%) was 0.39% (0.04-0.74).

Conclusions: National data reflect the presence of type 2 diabetes in U.S. adolescents, but the survey sample size was not large enough to obtain precise prevalence estimates because of the relatively low prevalence.

MeSH terms

  • Adolescent
  • Adult
  • Biomarkers / blood
  • Blood Glucose / analysis*
  • Body Mass Index
  • Child
  • Diabetes Mellitus / epidemiology*
  • Ethnicity
  • Female
  • Glucose Intolerance / epidemiology*
  • Glycated Hemoglobin / analysis
  • Glycated Hemoglobin / metabolism*
  • Health Surveys*
  • Humans
  • Male
  • Prevalence
  • Racial Groups
  • United States / epidemiology

Substances

  • Biomarkers
  • Blood Glucose
  • Glycated Hemoglobin A