Diffuse large cell lymphoma and t(8;22) (q24;q11) in a patient with idiopathic CD4+ T-lymphopenia

Leuk Lymphoma. 2001 Apr;41(3-4):421-3. doi: 10.3109/10428190109057998.

Abstract

We describe a unique case of a patient with a three-year history of idiopathic CD4(+) T cell lymphopenia (HIV negative) who presented with stage IV diffuse large cell non Hodgkin's lymphoma with t(8;22). Despite the severe lymphopenia, the patient tolerated intensive chemotherapy well and at 18 months, remains in complete remission.

Publication types

  • Case Reports

MeSH terms

  • Antibodies, Antinuclear / blood
  • Antineoplastic Combined Chemotherapy Protocols / administration & dosage
  • CD4-Positive T-Lymphocytes*
  • Chromosomes, Human, Pair 22*
  • Chromosomes, Human, Pair 8*
  • Humans
  • Lupus Coagulation Inhibitor / blood
  • Lymphoma, Large B-Cell, Diffuse / drug therapy
  • Lymphoma, Large B-Cell, Diffuse / etiology
  • Lymphoma, Large B-Cell, Diffuse / genetics*
  • Lymphopenia / blood
  • Lymphopenia / complications*
  • Lymphopenia / etiology*
  • Male
  • Middle Aged
  • Translocation, Genetic*

Substances

  • Antibodies, Antinuclear
  • Lupus Coagulation Inhibitor