Unmasking of deuterium kinetic isotope effects on the methane monooxygenase compound Q reaction by site-directed mutagenesis of component B

J Am Chem Soc. 2001 Oct 24;123(42):10421-2. doi: 10.1021/ja016632i.

Authors

B J Brazeau¹, B J Wallar, J D Lipscomb

Affiliation

¹ Department of Biochemistry, Molecular Biology, and Biophysics and Center for Metals in Biocatalysis University of Minnesota, Minneapolis 55455, USA.

PMID: 11604007
DOI: 10.1021/ja016632i

No abstract available

Publication types

Research Support, U.S. Gov't, P.H.S.

MeSH terms

Deuterium
Kinetics
Methane / metabolism
Mutagenesis, Site-Directed
Oxygenases / chemistry
Oxygenases / genetics*
Oxygenases / metabolism*

Substances

Deuterium
Oxygenases
methane monooxygenase
Methane

Grants and funding