Hereditary familial vestibular degenerative diseases

Ann N Y Acad Sci. 2001 Oct:942:493-6. doi: 10.1111/j.1749-6632.2001.tb03779.x.

Abstract

Identification of genes involved in hereditary vestibular disease is growing at a remarkable pace. Mutant mouse technology can be an important tool for understanding the biological mechanism of human vestibular diseases.

MeSH terms

  • Animals
  • Dyneins
  • Eye Movements
  • Humans
  • Immunohistochemistry
  • Mice
  • Mice, Mutant Strains
  • Myosin VIIa
  • Myosins / metabolism
  • Potassium Channels / genetics
  • Potassium Channels / physiology
  • Reflex, Vestibulo-Ocular
  • Shaker Superfamily of Potassium Channels
  • Vestibular Diseases / genetics*
  • Vestibular Diseases / metabolism
  • Vestibular Diseases / physiopathology

Substances

  • MYO7A protein, human
  • Myo7a protein, mouse
  • Myosin VIIa
  • Potassium Channels
  • Shaker Superfamily of Potassium Channels
  • Myosins
  • Dyneins