[Multidetector CT Angiography - is it a valuable screening tool to detect significant renal artery stenosis?]

Rofo. 2001 Dec;173(12):1086-92. doi: 10.1055/s-2001-18892.
[Article in German]

Abstract

Purpose: To evaluate the diagnostic value of multidetector CT angiography (MDCTA) of the renal arteries.

Methods: 27 patients underwent MDCTA of the renal arteries. Scan parameters were: collimation 4 x 1 mm, pitch 1.5, effective slice thickness 1.25 mm, reconstruction increment 0.8 mm, circulation time measurement, power injection of 80 ml iomeprol 400, flow 4 ml/sec. Independent reading on laser film was done by two radiologists using edited maximum intensity projections, multiplanar reconstructions and source images. Standard of reference was a 3D-FLASH MR angiography (1.5 T, 3.9/1.2, 10 degrees 0.2 mmol GdDTPA/kg bw) in 10 and intraarterial angiography in 17 patients.

Results: Analysing 63 arteries, sensitivity, specificity, positive predictive value and negative predictive value in terms of detection of moderate and high grade renal artery stenosis (n = 10) were 90, 98, 90 and 98 % for reader A, and 90 % each for reader B, respectively (kappa = 0.91 interobserver agreement). 1/11 accessory renal arteries was missed by both angiography and MDCTA. Image quality was graded as excellent or good in 26/27 of cases by both readers.

Conclusion: MDCTA proved to be a highly accurate tool in the detection of therapeutically relevant renal artery stenosis.

Publication types

  • Comparative Study

MeSH terms

  • Aged
  • Angiography*
  • Angiography, Digital Subtraction
  • Contrast Media
  • Female
  • Humans
  • Image Processing, Computer-Assisted
  • Imaging, Three-Dimensional
  • Iopamidol / analogs & derivatives*
  • Magnetic Resonance Angiography
  • Male
  • Mass Screening*
  • Middle Aged
  • Renal Artery Obstruction / diagnostic imaging*
  • Sensitivity and Specificity
  • Tomography, X-Ray Computed*

Substances

  • Contrast Media
  • iomeprol
  • Iopamidol