Successful allogeneic stem cell transplant after invasive pulmonary zygomycosis

M A Slavin; K Kannan; M R Buchanan; J Sasadeusz; A W Roberts

doi:10.1080/10428190290006305

Successful allogeneic stem cell transplant after invasive pulmonary zygomycosis

Leuk Lymphoma. 2002 Feb;43(2):437-9. doi: 10.1080/10428190290006305.

Authors

M A Slavin¹, K Kannan, M R Buchanan, J Sasadeusz, A W Roberts

Affiliation

¹ Department of Infectious Diseases, Victorian Infectious Diseases Service, Royal Melbourne Hospital, Parkville, Australia. slavinmonica@petermac.unimelb.edu.au

PMID: 11999584
DOI: 10.1080/10428190290006305

Abstract

We report the successful outcome of allogeneic stem cell transplant (SCT) in a patient with acute lymphoblastic leukaemia (ALL) and pulmonary zygomycosis diagnosed prior to transplant. The lesion was surgically excised and SCT proceeded with antifungal therapy, granulocyte transfusions and G-CSF support during the period of neutropenia.

Publication types

Case Reports

MeSH terms

Adult
Amphotericin B / administration & dosage
Antineoplastic Combined Chemotherapy Protocols / therapeutic use
Antineoplastic Combined Chemotherapy Protocols / toxicity
Disease-Free Survival
Humans
Lung Diseases, Fungal / chemically induced*
Lung Diseases, Fungal / diagnosis
Lung Diseases, Fungal / drug therapy
Male
Opportunistic Infections / chemically induced
Opportunistic Infections / diagnosis
Opportunistic Infections / drug therapy
Precursor Cell Lymphoblastic Leukemia-Lymphoma / complications
Precursor Cell Lymphoblastic Leukemia-Lymphoma / therapy*
Remission Induction
Stem Cell Transplantation*
Transplantation, Homologous
Treatment Outcome
Zygomycosis / chemically induced*
Zygomycosis / diagnosis
Zygomycosis / drug therapy

Substances

Amphotericin B