Successful allogeneic stem cell transplant after invasive pulmonary zygomycosis

Leuk Lymphoma. 2002 Feb;43(2):437-9. doi: 10.1080/10428190290006305.

Abstract

We report the successful outcome of allogeneic stem cell transplant (SCT) in a patient with acute lymphoblastic leukaemia (ALL) and pulmonary zygomycosis diagnosed prior to transplant. The lesion was surgically excised and SCT proceeded with antifungal therapy, granulocyte transfusions and G-CSF support during the period of neutropenia.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Amphotericin B / administration & dosage
  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use
  • Antineoplastic Combined Chemotherapy Protocols / toxicity
  • Disease-Free Survival
  • Humans
  • Lung Diseases, Fungal / chemically induced*
  • Lung Diseases, Fungal / diagnosis
  • Lung Diseases, Fungal / drug therapy
  • Male
  • Opportunistic Infections / chemically induced
  • Opportunistic Infections / diagnosis
  • Opportunistic Infections / drug therapy
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma / complications
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma / therapy*
  • Remission Induction
  • Stem Cell Transplantation*
  • Transplantation, Homologous
  • Treatment Outcome
  • Zygomycosis / chemically induced*
  • Zygomycosis / diagnosis
  • Zygomycosis / drug therapy

Substances

  • Amphotericin B