[Acute tubular necrosis with acute renal failure during the first month of treatment with 5-amino-salicylate (Pentasa(R))]

Gastroenterol Clin Biol. 2002 Apr;26(4):412-4.
[Article in French]

Abstract

We report a case of acute tubular necrosis in a patient with Crohn's disease treated by 5-amino-salicylate (Pentasa(R)) since one month. Normalization of renal biological parameters occurred rapidly after treatment withdrawal. This case raises the question of the optimal modalities of monitoring of renal function during treatment with 5-amino-salicylate.

Publication types

  • Case Reports
  • English Abstract

MeSH terms

  • Acute Kidney Injury / chemically induced*
  • Anti-Inflammatory Agents, Non-Steroidal / adverse effects*
  • Crohn Disease / complications
  • Crohn Disease / drug therapy
  • Humans
  • Kidney Tubules / drug effects
  • Kidney Tubules / pathology*
  • Male
  • Mesalamine / adverse effects*
  • Middle Aged
  • Necrosis

Substances

  • Anti-Inflammatory Agents, Non-Steroidal
  • Mesalamine