[Generalized mycobacterium avium infection in an infant (author's transl)]

Klin Padiatr. 1975 May;187(3):257-63.
[Article in German]

Abstract

In a 3-year-old girl, who was admitted to our hospital with marked splenomegaly, a swollen abdomen and progressive loss of weight, the difficulty in establishing the correct diagnosis, namely a very rare generalized infection with Mycobacterium avium (serum type III), and the lengthy course of the disease are demonstrated. Norcardiosis, sarcoidosis and BCG-granulomatosis were excluded. From the spleen, lymphatic nodes, gastric juice, stools and urine of the child, who had not been vaccinated with BCG vaccine, masses of acid-fast bacilli were isolated. The generalisation of the disease was promoted by an immunological deficiency. At autopsy an atrophic thymus was discovered. The extensive clinical and immunological investigations pointed to a partial deficiency of the cell-mediated immune systeme. The patient died 8 months after admission.

Publication types

  • Case Reports
  • English Abstract

MeSH terms

  • Anemia / etiology
  • Child, Preschool
  • Female
  • Humans
  • Immunologic Deficiency Syndromes / complications
  • Mycobacterium / isolation & purification*
  • Mycobacterium Infections / etiology
  • Mycobacterium Infections / microbiology*
  • Mycobacterium avium / isolation & purification*
  • Splenomegaly / etiology