Plexiform neurofibroma during and after pregnancy

Arch Gynecol Obstet. 2002 Nov;267(1):41-2. doi: 10.1007/s004040100239.

Abstract

Neurofibromatosis is a genetic disease that affects multiple organ systems, and has a wide range of clinical features. Neurofibromatosis in pregnancy is encountered with a frequency of 1:2434 to 1:18,500 deliveries. Plexiform neurofibromas are rare subcutaneous nodules or amorphous overgrowth of subcutaneous tissues, which may affect the underlying bone, and produce deformities. We present a patient with a giant plexiform neurofibroma of the thigh which got larger in pregnancy, and shrunk a bit in the postpartum period.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Diagnosis, Differential
  • Female
  • Humans
  • Neurofibroma, Plexiform / diagnosis*
  • Neurofibroma, Plexiform / pathology
  • Pregnancy
  • Pregnancy Complications, Neoplastic / diagnosis*
  • Pregnancy Complications, Neoplastic / pathology
  • Prenatal Care
  • Skin Neoplasms / diagnosis*
  • Skin Neoplasms / pathology
  • Thigh