Endothelial COX-2 induction by hypoxia liberates 6-keto-PGF1 alpha, a potent epithelial secretagogue

Adv Exp Med Biol. 2002:507:107-12. doi: 10.1007/978-1-4615-0193-0_17.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • 6-Ketoprostaglandin F1 alpha / metabolism*
  • Base Sequence
  • Cell Hypoxia / physiology*
  • Cell Line
  • Coculture Techniques
  • Cyclooxygenase 2
  • DNA Primers
  • Endothelium, Vascular / enzymology*
  • Enzyme Induction
  • Epithelial Cells / physiology*
  • Humans
  • Isoenzymes / biosynthesis
  • Isoenzymes / genetics*
  • Membrane Proteins
  • Prostaglandin-Endoperoxide Synthases / biosynthesis
  • Prostaglandin-Endoperoxide Synthases / genetics*
  • Respiratory Mucosa / physiology
  • Umbilical Veins
  • Urothelium / physiology

Substances

  • DNA Primers
  • Isoenzymes
  • Membrane Proteins
  • 6-Ketoprostaglandin F1 alpha
  • Cyclooxygenase 2
  • PTGS2 protein, human
  • Prostaglandin-Endoperoxide Synthases