Squamous cell carcinoma of the head and neck in Ontario, Canada, and in southeastern Norway

Laryngoscope. 2003 Apr;113(4):695-701. doi: 10.1097/00005537-200304000-00021.

Abstract

Objectives/hypothesis: Reports comparing case mix, treatments, and outcomes between different countries are uncommon in head and neck oncology. Prospective databases of unselected patients from regional cancer centers in southeastern Ontario, Canada, and southeastern Norway were compared.

Study design: Retrospective comparative study of two prospective databases.

Methods: The case mix, treatments, and disease-specific mortality were compared using frequency tables, Kaplan-Meier survival curves, and the log rank test. RESULTSThe case mix, except for differences in oral cavity, oropharynx, and the recorded tumor (T) category, was similar, and the treatments were different. There was no statistical difference in overall survival for all patients, as well as for some sites.

Conclusions: The results of treatments, based on different overall treatment polices, for all patients were similar. The differences in recorded T category with no statistical difference in overall survival suggest a difference in staging assignment and raises a question about the reliability of the TNM staging process.

MeSH terms

  • Adult
  • Canada / epidemiology
  • Carcinoma, Squamous Cell / mortality*
  • Carcinoma, Squamous Cell / pathology*
  • Carcinoma, Squamous Cell / therapy
  • Catchment Area, Health
  • Databases as Topic
  • Female
  • Head and Neck Neoplasms / mortality*
  • Head and Neck Neoplasms / pathology*
  • Head and Neck Neoplasms / therapy
  • Humans
  • Male
  • Neoplasm Staging
  • Norway / epidemiology
  • Ontario / epidemiology
  • Prospective Studies
  • Survival Rate