Right hippocampal sclerosis is more common than left after febrile seizures

Neurology. 2003 Apr 8;60(7):1209-10. doi: 10.1212/01.wnl.0000052823.29467.a0.

Abstract

Temporal lobe epilepsy (TLE) is frequently associated with hippocampal sclerosis (HS) and a history of febrile convulsions (HFC). The authors investigated 292 patients with TLE due to HS. Left HS occurred more frequently (57%) than right HS (43%, p = 0.01). Forty-seven percent of the patients had HFC. In patients with right HS, HFC occurred in 59.6%, whereas in patients with left HS, HFC was present in 37.5%, showing a highly significant lateralization difference.

Publication types

  • Clinical Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Age of Onset
  • Comorbidity
  • Epilepsy, Temporal Lobe / diagnosis*
  • Epilepsy, Temporal Lobe / epidemiology
  • Female
  • Functional Laterality
  • Hippocampus / pathology*
  • Humans
  • Magnetic Resonance Imaging
  • Male
  • Middle Aged
  • Risk Factors
  • Sclerosis / diagnosis*
  • Sclerosis / epidemiology
  • Seizures, Febrile / epidemiology*
  • Sex Distribution