[Soluble interleukin 2 receptor (SIL-2R) in bronchoalveolar lavage fluid (BALF) of patients with sarcoidosis and atopic bronchial asthma]

Pneumonol Alergol Pol. 2002;70(7-8):347-52.
[Article in Polish]

Abstract

The aim of the study was assessment of sIL-2R in BALF in asthma and sarcoidosis patients. Forty three patients were enrolled in this study. Twenty eight with sarcoidosis (S) in different stages (I, II, III) and activity of disease: active (AS) or nonactive (NAS) and fifteen with atopic bronchial asthma (AO). BALF sIL-2R levels were measured in both groups. The level of sIL-2R was similar in sarcoidosis patients independently to activity of disease. Significantly lower level of sII-2R in BALF was observed in patients with AO in comparison to S, SII and NAS (p < 0.005). We didn't find significant differences in sIL-2R levels between AO and SI, SIII, AS.

Publication types

  • Comparative Study
  • English Abstract

MeSH terms

  • Adult
  • Asthma / immunology
  • Asthma / metabolism*
  • Biomarkers / analysis
  • Bronchoalveolar Lavage Fluid / chemistry*
  • Bronchoalveolar Lavage Fluid / immunology
  • Chi-Square Distribution
  • Female
  • Humans
  • Male
  • Middle Aged
  • Receptors, Interleukin-2 / analysis*
  • Sarcoidosis, Pulmonary / immunology
  • Sarcoidosis, Pulmonary / metabolism*
  • Solubility
  • Statistics, Nonparametric

Substances

  • Biomarkers
  • Receptors, Interleukin-2