In B-cell chronic lymphocytic leukemias, 7q21 translocations lead to overexpression of the CDK6 gene

Blood. 2003 Aug 15;102(4):1549-50. doi: 10.1182/blood-2003-04-1220.
No abstract available

Publication types

  • Letter

MeSH terms

  • Aged
  • Chromosomes, Human, Pair 7 / genetics*
  • Cyclin-Dependent Kinase 6
  • Cyclin-Dependent Kinases / biosynthesis
  • Cyclin-Dependent Kinases / genetics*
  • Gene Expression Regulation, Leukemic
  • Gene Rearrangement
  • Humans
  • In Situ Hybridization, Fluorescence
  • Leukemia, Lymphocytic, Chronic, B-Cell / genetics*
  • Leukemia, Lymphocytic, Chronic, B-Cell / metabolism
  • Male
  • Middle Aged
  • Translocation, Genetic / genetics

Substances

  • CDK6 protein, human
  • Cyclin-Dependent Kinase 6
  • Cyclin-Dependent Kinases