Abstract
A case of retinoic acid embryopathy which was retrospectively diagnosed after delivery is presented. The affected fetus was exposed to the drug during the first month of pregnancy and second-trimester sonographic examination showed hydrocephalus and cardiac malformation. The diagnosis was made on the basis of autopsy findings and genetic enquiry.
MeSH terms
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Abnormalities, Multiple / chemically induced*
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Abnormalities, Multiple / diagnostic imaging
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Abortion, Therapeutic
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Adult
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Facial Bones / abnormalities
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Female
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Heart Defects, Congenital / chemically induced
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Heart Defects, Congenital / diagnostic imaging
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Humans
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Hydrocephalus / chemically induced
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Hydrocephalus / diagnostic imaging
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Maternal-Fetal Exchange
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Pregnancy
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Pregnancy Trimester, Second
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Tretinoin / adverse effects*
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Ultrasonography, Prenatal*