[Linezolid in two premature babies with necrotizing enterocolitis and infection with vancomycin-resistant enterococcus]

Klin Padiatr. 2004 Jan-Feb;216(1):21-3. doi: 10.1055/s-2004-817683.
[Article in German]

Abstract

The use of the antibiotic Linezolid in two premature babies with necrotizing enterocolitis and infection with vancomycin-resistant enterococcus is described. Therapy with Linezolid in cause of necrotizing enterocolitis is an exception. Actually there are no proven recommendations for the use in this age group. Despite the successfully results more investigations for the use of linezolid in newborns and prematures are necessary.

Publication types

  • Case Reports
  • English Abstract

MeSH terms

  • Acetamides / administration & dosage*
  • Acetamides / pharmacokinetics
  • Anti-Bacterial Agents
  • Anti-Infective Agents / administration & dosage*
  • Anti-Infective Agents / pharmacokinetics
  • Dose-Response Relationship, Drug
  • Drug Administration Schedule
  • Drug Resistance, Multiple
  • Drug Therapy, Combination / therapeutic use
  • Enterococcus faecium* / drug effects
  • Enterocolitis, Necrotizing / drug therapy*
  • Enterocolitis, Necrotizing / microbiology
  • Female
  • Gestational Age
  • Gram-Positive Bacterial Infections / drug therapy*
  • Humans
  • Ileostomy
  • Infant, Newborn
  • Infant, Premature, Diseases / drug therapy*
  • Infant, Premature, Diseases / microbiology
  • Infant, Small for Gestational Age*
  • Infusions, Intravenous
  • Jejunostomy
  • Linezolid
  • Male
  • Microbial Sensitivity Tests
  • Oxazolidinones / administration & dosage*
  • Oxazolidinones / pharmacokinetics
  • Postoperative Complications / drug therapy
  • Treatment Outcome
  • Vancomycin Resistance*

Substances

  • Acetamides
  • Anti-Bacterial Agents
  • Anti-Infective Agents
  • Oxazolidinones
  • Linezolid