Epidemiologic study of the association between human T-cell lymphotropic virus type 1 and Strongyloides stercoralis infection in female blood donors (Guadeloupe, French West Indies)

West Indian Med J. 2004 Jan;53(1):3-6.

Abstract

This case control study was conducted among female blood donors in Guadeloupe. A total of 85 HTLV-1 positive subjects were matched by age (+/- 5 years) in a 1:3 ratio to 255 HTLV-1 negative controls. The mean age was 48.5 and 48.9 years respectively. Ethnic, environmental and socio-economic risk factors were studied. Four risk factors were found independently associated with HTLV-1 seropositivity: Strongyloides stercoralis antibodies (OR = 3.6, CI 1.8, 7.3), low socio-economic status (OR = 2.0 CI 1.0, 4.0), low educational level (OR = 2.0 CI 1.0, 4.0) and agricultural activity (OR = 2.8 CI 1.4, 5.6). This logistic regression analysis demonstrates the reality of the association between HTLV-1 carriers and Strongyloides stercoralis, and its association with socio-economic and environmental risk factors.

MeSH terms

  • Animals
  • Antibodies, Helminth / blood
  • Antibodies, Viral / blood
  • Blood Donors*
  • Case-Control Studies
  • Female
  • Guadeloupe / epidemiology
  • HTLV-I Infections / complications*
  • HTLV-I Infections / epidemiology
  • Human T-lymphotropic virus 1 / immunology
  • Humans
  • Middle Aged
  • Risk Factors
  • Seroepidemiologic Studies
  • Socioeconomic Factors
  • Strongyloides stercoralis* / immunology
  • Strongyloidiasis / complications*
  • Strongyloidiasis / epidemiology

Substances

  • Antibodies, Helminth
  • Antibodies, Viral