Liver transplantation for treatment of metastatic neuroendocrine tumors

Ann N Y Acad Sci. 2004 Apr:1014:265-9. doi: 10.1196/annals.1294.029.

Abstract

Liver transplantation can be considered a therapeutic option for patients with neuroendocrine tumors only metastatic to the liver. Important selection criteria are well-differentiated tumors and a low proliferation rate (Ki67 <10%). In this series, orthopic liver transplantation offered good relief of symptoms and long disease-free intervals with initial survival of grafts and patients as in benign disease. The experience with multivisceral transplantation is still limited.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Carcinoid Tumor / pathology
  • Female
  • Follow-Up Studies
  • Humans
  • Insulinoma / pathology
  • Liver Neoplasms / mortality
  • Liver Neoplasms / secondary*
  • Liver Neoplasms / surgery*
  • Liver Transplantation*
  • Male
  • Middle Aged
  • Neuroendocrine Tumors / mortality
  • Neuroendocrine Tumors / secondary*
  • Neuroendocrine Tumors / surgery*
  • Pancreatic Neoplasms / pathology
  • Survival Rate