Primary central nervous system angiitis, amyloid angiopathy, and Alzheimer's pathology presenting with Balint's syndrome

Surv Ophthalmol. 2004 Jul-Aug;49(4):454-9. doi: 10.1016/j.survophthal.2004.04.002.

Abstract

We report a patient who presented with Balint's syndrome as a manifestation of primary central nervous system angiitis. Clinical findings included simultanagnosia, optic ataxia, and optic apraxia. Pathologic evaluation demonstrated amyloid angiopathy and Alzheimer's plaques. The presence of primary central nervous system angiitis along with amyloid angiopathy and Alzheimer's plaques may not be coincidental. Angiitis may be a foreign body reaction to A4 amyloid deposition.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Aged, 80 and over
  • Agnosia / diagnosis
  • Agnosia / drug therapy
  • Agnosia / etiology*
  • Alzheimer Disease / complications*
  • Alzheimer Disease / diagnosis
  • Alzheimer Disease / drug therapy
  • Apraxias / diagnosis
  • Apraxias / drug therapy
  • Apraxias / etiology*
  • Ataxia / diagnosis
  • Ataxia / drug therapy
  • Ataxia / etiology*
  • Cerebral Amyloid Angiopathy / complications*
  • Cerebral Amyloid Angiopathy / diagnosis
  • Cerebral Amyloid Angiopathy / drug therapy
  • Female
  • Glucocorticoids / therapeutic use
  • Humans
  • Magnetic Resonance Imaging
  • Optic Nerve Diseases / diagnosis
  • Optic Nerve Diseases / drug therapy
  • Optic Nerve Diseases / etiology
  • Syndrome
  • Vasculitis, Central Nervous System / complications*
  • Vasculitis, Central Nervous System / diagnosis
  • Vasculitis, Central Nervous System / drug therapy

Substances

  • Glucocorticoids