As normal as normal can be?

Nat Genet. 2004 Sep;36(9):931-2. doi: 10.1038/ng0904-931.

Abstract

Two papers report that large-scale copy-number variations, ranging in size from 100 kb to 2 Mb, are distributed widely throughout the human genome, and that a high proportion of them encompass known genes. This unexpected level of genome variation has implications for our view of human genetic diversity and phenotypic variation.

Publication types

  • Comment
  • News

MeSH terms

  • Gene Dosage*
  • Genetic Variation*
  • Genome, Human*
  • Humans
  • Phenotype