[Facial palsy and central nervous system infection with varicella virus following adult chickenpox]

Rev Neurol (Paris). 2004 Oct;160(10):980-2. doi: 10.1016/s0035-3787(04)71135-2.
[Article in French]

Abstract

Introduction: VZV virus-related peripheral neuropathies usually occur after shingles in adults and more rarely after chickenpox in childhood.

Case report: A 54-year-old patient presented with a right VIIth nerve palsy following a chickenpox rash and recovered after antiviral treatment. CSF analysis revealed lymphocytic meningitis and the virus was identified by PCR.

Conclusions: Although previous chickenpox was not found in the patient's past history, the probability of reinfection is likely. The virus can be assumed to affect the nervous system directly; the axonal or demyelinating mechanism of the neuropathy may be discussed.

Publication types

  • Case Reports
  • English Abstract

MeSH terms

  • Acyclovir / therapeutic use
  • Antiviral Agents / therapeutic use
  • Chickenpox / complications*
  • Chickenpox / drug therapy
  • Chickenpox / physiopathology
  • Demyelinating Diseases / etiology
  • Demyelinating Diseases / pathology
  • Facial Nerve Diseases / drug therapy
  • Facial Nerve Diseases / etiology*
  • Facial Paralysis / drug therapy
  • Facial Paralysis / etiology*
  • Facial Paralysis / physiopathology
  • Herpesvirus 3, Human*
  • Humans
  • Male
  • Meningitis / drug therapy
  • Meningitis / etiology
  • Middle Aged

Substances

  • Antiviral Agents
  • Acyclovir