Prenatal ultrasound detection of bilateral focal polymicrogyria

Prenat Diagn. 2004 Oct;24(10):808-11. doi: 10.1002/pd.987.

Abstract

Objectives: Prenatal diagnosis by ultrasound of fetal polymicrogyria has been reported only once.

Methods: We describe an additional case of polymicrogyria in a fetus from a monozygotic twin pair, probably the consequence of twin-to-twin transfusion syndrome.

Results: On ultrasound, there were bilateral cortical hyperechogenic spots, and prenatal magnetic resonance imaging demonstrated the typical features of bilateral focal polymicrogyria.

Conclusion: Polymicrogyria can be considered in the differential diagnosis of hyperechogenic brain lesions on fetal ultrasound. We also confirm the risk of brain damage in monochorionic twins pregnancies and the likely hypoxic-ischemic etiology of polymicrogyria.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Female
  • Fetofetal Transfusion / complications*
  • Frontal Lobe / abnormalities*
  • Frontal Lobe / diagnostic imaging
  • Frontal Lobe / embryology
  • Humans
  • Magnetic Resonance Imaging
  • Nervous System Malformations / diagnosis
  • Nervous System Malformations / diagnostic imaging*
  • Nervous System Malformations / embryology
  • Nervous System Malformations / etiology
  • Parietal Lobe / abnormalities*
  • Parietal Lobe / diagnostic imaging
  • Parietal Lobe / embryology
  • Pregnancy
  • Twins, Monozygotic*
  • Ultrasonography, Prenatal*