A novel pyrrole synthesis

Org Biomol Chem. 2004 Nov 7;2(21):3060-2. doi: 10.1039/B412206B. Epub 2004 Sep 21.

Abstract

The silver(I)-promoted oxidative cyclization of homopropargylamines at room temperature provides a novel access to pyrroles. Homopropargylamines are readily available by the addition of a propargyl Grignard reagent to Schiff bases.