Di- and tri-alkylphosphine adducts of S-donor palladacycles as catalysts in the Suzuki coupling of aryl chlorides

Robin B Bedford; Catherine S J Cazin; Michael B Hursthouse; Mark E Light; Véronique J M Scordia

doi:10.1039/B407922C

Di- and tri-alkylphosphine adducts of S-donor palladacycles as catalysts in the Suzuki coupling of aryl chlorides

Dalton Trans. 2004 Nov 21:(22):3864-8. doi: 10.1039/B407922C. Epub 2004 Oct 22.

Authors

Robin B Bedford¹, Catherine S J Cazin, Michael B Hursthouse, Mark E Light, Véronique J M Scordia

Affiliation

¹ Department of Chemistry, University of Exeter, Exeter EX4 4QD, UK. r.bedford@ex.ac.uk

PMID: 15540130
DOI: 10.1039/B407922C

Abstract

The reaction of tricyclohexylphosphine with the S-based palladacycle [(Pd(mu-OAc)(kappa2-S,C-C(6)H(4)CH(2)SMe))(2)] gives several products, regardless of stoichiometry, one of which, [Pd(kappa1-OAc)(eta1-C(6)H(4)CH(2)SMe)(PCy3)2], has been characterised crystallographically. Despite this, catalysts formed in situ from di- and tri-alkylphosphines and [(Pd(mu-OAc)(kappa2-S,C-C(6)H(4)CH(2)SMe))2] show excellent activity in the Suzuki coupling of a range of deactivated, non-activated and activated aryl chloride substrates.