Effect of hormone therapy on mortality rates among women with heart failure and coronary artery disease

Kirsten Bibbins-Domingo; Feng Lin; Eric Vittinghoff; Elizabeth Barrett-Connor; Stephen B Hulley; Deborah Grady; Michael G Shlipak

doi:10.1016/j.amjcard.2004.09.021

Effect of hormone therapy on mortality rates among women with heart failure and coronary artery disease

Am J Cardiol. 2005 Jan 15;95(2):289-91. doi: 10.1016/j.amjcard.2004.09.021.

Authors

Kirsten Bibbins-Domingo¹, Feng Lin, Eric Vittinghoff, Elizabeth Barrett-Connor, Stephen B Hulley, Deborah Grady, Michael G Shlipak

Affiliation

¹ Division of General Internal Medicine, San Francisco General Hospital, University of California-San Francisco, San Francisco, CA 94143, USA. bibbinsk@medicine.ucsf.edu

PMID: 15642574
DOI: 10.1016/j.amjcard.2004.09.021

Abstract

Randomized, controlled trial data from the Heart and Estrogen-progestin Replacement Study were used to evaluate the effect of estrogen plus progestin use on all-cause mortality in women with heart failure and coronary disease. Over the 4.1-year follow-up, estrogen plus progestin use had no effect on all-cause mortality (hazard ratio 1.0, 95% confidence interval 0.7 to 1.4, p = 0.8) in women with heart failure and coronary disease.

MeSH terms

Aged
California / epidemiology
Coronary Artery Disease / complications
Coronary Artery Disease / epidemiology
Coronary Artery Disease / mortality*
Coronary Artery Disease / prevention & control*
Estrogen Replacement Therapy*
Estrogens, Conjugated (USP) / administration & dosage
Female
Follow-Up Studies
Heart Failure / complications
Heart Failure / epidemiology
Heart Failure / mortality*
Heart Failure / prevention & control*
Humans
Medroxyprogesterone / administration & dosage
Proportional Hazards Models
Randomized Controlled Trials as Topic
Survival Analysis

Substances

Estrogens, Conjugated (USP)
Medroxyprogesterone