Attention and memory functioning among pediatric patients with medulloblastoma

J Pediatr Psychol. 2006 Apr;31(3):272-80. doi: 10.1093/jpepsy/jsj019. Epub 2005 Mar 23.

Abstract

Objective: To test the hypotheses that memory and attention deficits are prevalent in survivors of childhood medulloblastoma (MB) and that these deficits are associated with problems with academic achievement.

Methods: The medical charts of 38 child survivors of MB, who were administered the California Verbal Learning Test, Child Version (CVLT-C), Conners' Continuous Performance Test (CPT), and the Wechsler Individual Achievement Test (WIAT) as part of a comprehensive neurocognitive test battery, were retrospectively reviewed.

Results: Although no significant verbal memory deficits were found, 8 of 11 CPT variables were significantly below the standardization mean (p < or = .01). Additionally, stepwise regression analyses found that increased omission errors were significantly associated with lower reading and math performance (p < or = .01).

Conclusions: These findings confirm previous reports of attention deficits among survivors of MB and provide a better understanding of how the dysfunction of particular attentional substrates (e.g., perceptual sensitivity, response bias) may result in learning problems in this population.

MeSH terms

  • Adolescent
  • Attention*
  • Cerebellar Neoplasms / psychology
  • Cerebellar Neoplasms / rehabilitation*
  • Child
  • Child, Preschool
  • Educational Status
  • Female
  • Humans
  • Male
  • Medulloblastoma / psychology
  • Medulloblastoma / rehabilitation*
  • Memory*
  • Multivariate Analysis
  • Neuropsychological Tests
  • Regression Analysis
  • Retrospective Studies
  • Survivors / psychology*