Determinants of failure of brachiocephalic elbow fistulas for haemodialysis

Eur J Vasc Endovasc Surg. 2005 Aug;30(2):209-14. doi: 10.1016/j.ejvs.2005.04.009.

Abstract

Objectives: The aim of this study was to analyse the results of brachiocephalic fistulas for haemodialysis and to determine possible predictors of failure.

Patients and methods: Between April 1999 and September 2004, a consecutive series of 100 autologous brachiocephalic fistulas were created in 96 patients. There were 57 men and 39 women with a mean (SD) age of 59.2 (15.6) years. Data were prospectively gathered.

Results: The mean (SD) follow-up was 20.1 (16.4) months. The primary, primary assisted, and secondary patency rates after 6 months were 73.4, 83.2 and 86.4%, respectively. After 1 year, these figures were 54.7, 72.3 and 79.2%, and after 2 years 40.4, 59.2 and 67.5%, respectively. Predictors of failure with regard to primary patency, determined with Cox regression multivariate analysis, included diabetes mellitus (HR 2.81, p < 0.001) and a history of contralateral PTFE loop graft (HR 7.79, p = 0.007).

Conclusion: Primary patency of brachiocephalic fistulas is comparable to that of radiocephalic fistulas. Primary assisted and secondary patency rates can, however, be brought to a much higher level, especially in patients without diabetes and a large-diameter venous outflow tract.

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Arteriovenous Shunt, Surgical*
  • Brachiocephalic Trunk / surgery*
  • Brachiocephalic Veins / surgery*
  • Elbow / blood supply
  • Elbow / surgery
  • Female
  • Follow-Up Studies
  • Humans
  • Male
  • Middle Aged
  • Prospective Studies
  • Renal Dialysis*
  • Renal Insufficiency / therapy*
  • Risk Factors
  • Treatment Failure
  • Vascular Patency