Focus group methodology uses focused interviews to obtain information from individuals and interactions among individuals in a small group setting. In this article we share the insights we have gained from using focus group methodology in work with an under-served population of black menopausal women. This methodology holds promise for advancing our understanding of, and ultimately eliminating, health disparities. Included is a discussion of planning and facilitating the focus group, recruiting group members, collecting and analyzing the data and reporting the results. Throughout, we explain how we applied these principles and we conclude by sharing lessons learned from our study on menopause and midlife experiences in Black women.