[Characteristics of changes in respiratory function of humans after a long stay in Antarctic region]

Fiziol Zh (1994). 2005;51(3):25-31.
[Article in Ukrainian]

Abstract

Fifteen participants of the Antarctic expedition (men, 27-51 years old) have been investigated after their return from a one-year stay there. All subjects have signs of latent hypoxia. Compensation of hypoxic reactions depended on the initial state of organism oxygen regimen as well as on the features of a genotype. It was supposed that, after a long stay by a person in the coastal Antarctic conditions, the latent form of hypoxia could develop. The latter was accompanied by reorganizations of oxygen regimen and determined by specific features of a genotype.

MeSH terms

  • Adaptation, Physiological / genetics
  • Adaptation, Physiological / physiology*
  • Adult
  • Antarctic Regions
  • Blood Volume / physiology
  • DNA-Binding Proteins / genetics
  • Exercise Test
  • Genotype
  • Hemodynamics / physiology
  • Humans
  • Hypoxia / blood
  • Hypoxia / physiopathology*
  • Hypoxia-Inducible Factor 1
  • Hypoxia-Inducible Factor 1, alpha Subunit
  • Male
  • Middle Aged
  • Nuclear Proteins / genetics
  • Oxidative Stress / physiology
  • Oxygen / blood*
  • Polymorphism, Genetic
  • Pulmonary Gas Exchange / physiology*
  • Transcription Factors / genetics

Substances

  • DNA-Binding Proteins
  • HIF1A protein, human
  • Hypoxia-Inducible Factor 1
  • Hypoxia-Inducible Factor 1, alpha Subunit
  • Nuclear Proteins
  • Transcription Factors
  • Oxygen