Independent clones at separable stages of differentiation, bearing different GATA1 mutations, in the same TMD patient with Down syndrome

Blood. 2005 Sep 1;106(5):1887-8. doi: 10.1182/blood-2005-03-1071.
No abstract available

Publication types

  • Case Reports
  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Antigens, CD34 / biosynthesis
  • Cell Differentiation / physiology
  • Clone Cells
  • DNA-Binding Proteins / genetics*
  • Down Syndrome / complications*
  • Down Syndrome / genetics*
  • Erythroid-Specific DNA-Binding Factors
  • Female
  • GATA1 Transcription Factor
  • Humans
  • Infant, Newborn
  • Megakaryocytes / physiology
  • Mutation
  • Myeloproliferative Disorders / complications*
  • Myeloproliferative Disorders / genetics*
  • Reverse Transcriptase Polymerase Chain Reaction
  • Transcription Factors / genetics*

Substances

  • Antigens, CD34
  • DNA-Binding Proteins
  • Erythroid-Specific DNA-Binding Factors
  • GATA1 Transcription Factor
  • GATA1 protein, human
  • Transcription Factors

Grants and funding