[Lemierre syndrome variant: Hepatic abscesses and hepatic venous thrombosis due to Fusobacterium nucleatum septicemia]

Rev Med Interne. 2006 Jun;27(6):482-6. doi: 10.1016/j.revmed.2005.12.013. Epub 2006 Jan 18.
[Article in French]

Abstract

Introduction: Like Fusobacterium necrophorum, Fusobacterium nucleatum is capable causing Lemierre's syndrome. Various locations of venous thrombosis have been described associated with Fusobacterium sp. septicemia.

Exegesis: We describe a 43-year old alcoholic patient with F.nucleatum septicemia complicated with hepatic abscesses, middle hepatic venous thrombosis, osteomyelitis and infiltrative pneumonia. A pancreatic prosthesis was the only potentially identified infectious entrance.

Conclusion: Our patient showed an alternative presentation of Lemierre's syndrome, a "digestive variant". To the best of our knowledge, this is the first report of Fusobacterium septicemia associated with hepatic venous thrombosis. This report is close to the cases of portal thrombosis and opens the clinical sphere of the lemierre's syndrome, whose incidence is increasing.

Publication types

  • Case Reports
  • English Abstract

MeSH terms

  • Adult
  • Amoxicillin / therapeutic use
  • Anti-Bacterial Agents / therapeutic use
  • Budd-Chiari Syndrome / diagnosis
  • Budd-Chiari Syndrome / microbiology*
  • Budd-Chiari Syndrome / therapy
  • Fusobacterium Infections / complications*
  • Fusobacterium Infections / diagnosis
  • Fusobacterium Infections / therapy
  • Fusobacterium nucleatum / isolation & purification*
  • Humans
  • Liver Abscess / diagnosis
  • Liver Abscess / microbiology*
  • Liver Abscess / therapy
  • Male
  • Pancreas / surgery
  • Prostheses and Implants / adverse effects
  • Sepsis / diagnosis
  • Sepsis / microbiology*
  • Sepsis / therapy
  • Syndrome
  • Treatment Outcome

Substances

  • Anti-Bacterial Agents
  • Amoxicillin