The identification of three novel MICA alleles by sequence-based typing

Tissue Antigens. 2006 Apr;67(4):321-5. doi: 10.1111/j.1399-0039.2006.00574.x.

Abstract

During a study of MICA frequency in a healthy population and a cohort of patients suffering with inflammatory bowel disease, three DNA samples produced unusual reactivity patterns using polymerase chain reaction sequence-specific primers (PCR-SSP). These samples were subsequently characterized by sequence-based typing (SBT). Here, we report the sequence of these three novel MICA alleles.

Publication types

  • Comparative Study

MeSH terms

  • Alleles*
  • Base Sequence
  • Case-Control Studies
  • Cohort Studies
  • DNA / genetics
  • DNA Primers
  • Histocompatibility Antigens Class I / genetics*
  • Humans
  • Inflammatory Bowel Diseases / genetics*
  • Molecular Sequence Data
  • Polymerase Chain Reaction
  • Sequence Homology, Nucleic Acid

Substances

  • DNA Primers
  • Histocompatibility Antigens Class I
  • MHC class I-related chain A
  • DNA