[Association between microalbuminuria and arterial stiffness in hypertensive and diabetic patients]

Zhonghua Xin Xue Guan Bing Za Zhi. 2006 May;34(5):387-90.
[Article in Chinese]

Abstract

Objective: To investigate the relationship between microalbuminuria and arterial compliance in hypertensive and diabetes patients.

Methods: A total of 200 patients with essential hypertension and/or diabetes were studied. Albumin/creatinine ratio (ACR) was determined. Carotid to femoral Pulse Wave Velocity (PWV), C(1) and C(2) were measured by a Complier Colson device and DO-2020, respectively.

Result: (1) C(1) and C(2) were lower and PWV higher in high ACR group than in normal ACR group (P < 0.01). (2) In patients younger than 60 years, C(1) was lower and PWV higher in high ACR group than that in normal ACR group (P < 0.01). In patients older than 60 years, C(1), C(2) were lower in high ACR group than in normal ACR group.

Conclusion: The results indicated that compliance of large and small vessels in hypertensive and diabetic patients decreased with increasing ACR.

Publication types

  • English Abstract

MeSH terms

  • Adult
  • Aged
  • Albumins / analysis
  • Albuminuria*
  • Arteries / physiopathology
  • Creatinine / urine
  • Diabetes Mellitus / physiopathology*
  • Diabetes Mellitus / urine*
  • Elasticity
  • Female
  • Humans
  • Hypertension / physiopathology*
  • Hypertension / urine*
  • Male
  • Middle Aged

Substances

  • Albumins
  • Creatinine