[Lambert-Eaton myastenic syndrome revealing neuroblastoma in 2 children]

E Bosdure; S Attarian; J Mancini; Y Mikaeloff; B Chabrol

doi:10.1016/j.arcped.2006.04.019

[Lambert-Eaton myastenic syndrome revealing neuroblastoma in 2 children]

Arch Pediatr. 2006 Aug;13(8):1121-4. doi: 10.1016/j.arcped.2006.04.019. Epub 2006 Jun 21.

[Article in French]

Authors

E Bosdure¹, S Attarian, J Mancini, Y Mikaeloff, B Chabrol

Affiliation

¹ Service de neurologie pédiatrique et unité de médecine infantile, CHU Timone-Enfant, 385, rue Saint-Pierre, 13385 Marseille cedex 05, France.

PMID: 16793244
DOI: 10.1016/j.arcped.2006.04.019

Abstract

Lambert-Eaton myasthenic syndrome is a paraneoplasic syndrome which can reveal a primitive tumor. Frequently, the first diagnosis is myasthenia gravis. This disease is extremely rare in children. Only 10 cases have been reported in the last 35 years. We report 2 new observations occurring in very young patients, aged 2 and 3 years, with a ganglioneurobastoma as primitive tumor.

Publication types

Case Reports

MeSH terms

Brain Neoplasms / diagnosis*
Brain Neoplasms / diagnostic imaging
Brain Neoplasms / surgery
Child, Preschool
Fatal Outcome
Female
Ganglioneuroblastoma / diagnosis*
Ganglioneuroblastoma / diagnostic imaging
Ganglioneuroblastoma / surgery
Humans
Lambert-Eaton Myasthenic Syndrome / etiology*
Male
Radiography
Treatment Outcome