[Endothelial dysfunction assessment using vascular ultrasound in heart failure patients]

Rev Med Chir Soc Med Nat Iasi. 2006 Oct-Dec;110(4):816-23.
[Article in Romanian]

Abstract

Endothelial dysfunction is an important factor leading to atherosclerosis, hypertension and heart failure. Flow mediated dilatation (endothelium dependent function) can be evaluated by vascular ultrasound. We investigated 71 heart failure patients (36 men-50.7%, 35 women-49.3%). The evaluation methods were: electrocardiogram, vascular ultrasound, echocardiography, chest X ray, hematological and biochemical tests. The statistical correlations were performed between clinical data, morphologic and hemodynamic parameters. Our results showed that endothelial dysfunction was present in all heart failure patients but it did not correlate with hemodynamic parameters. Elastic arterial parameters variation correlated with heart failure severity and flow mediated vasodilation.

MeSH terms

  • Aged
  • Aged, 80 and over
  • Biomarkers / blood
  • Echocardiography
  • Elasticity
  • Electrocardiography
  • Endothelium, Vascular / diagnostic imaging*
  • Endothelium, Vascular / physiopathology*
  • Female
  • Heart Failure / blood
  • Heart Failure / diagnostic imaging*
  • Heart Failure / physiopathology*
  • Humans
  • Male
  • Middle Aged
  • Retrospective Studies
  • Risk Assessment
  • Ultrasonography, Interventional*
  • Vascular Resistance

Substances

  • Biomarkers