Cytogenetic analysis of two sacral chordomas

D L Persons; J A Bridge; J R Neff

doi:10.1016/0165-4608(91)90171-p

Cytogenetic analysis of two sacral chordomas

Cancer Genet Cytogenet. 1991 Oct 15;56(2):197-201. doi: 10.1016/0165-4608(91)90171-p.

Authors

D L Persons¹, J A Bridge, J R Neff

Affiliation

¹ Department of Pathology and Oncology, University of Kansas Medical Center.

PMID: 1756464
DOI: 10.1016/0165-4608(91)90171-p

Abstract

Cytogenetic analysis of two sacral chordomas revealed two distinct abnormal clones in one of the cases: 44,XY,t(1;3)(q42;q11), -2,der(7)t(2;7)(q23;q32), -21 and 46,X,t(Y;8)(q12;q22), t(1;14)(p34;q32),t(5;10)(q13;p11). All cells analyzed from the second case were cytogenetically normal. To the best of our knowledge, chordomas have not previously been subjected to cytogenetic analysis.

Publication types

Case Reports
Research Support, Non-U.S. Gov't

MeSH terms

Aged
Bone Neoplasms / genetics*
Chordoma / genetics*
Chromosomes, Human
Female
Humans
Male
Middle Aged
Sacrum*
Translocation, Genetic*
Y Chromosome