Platinum(II)-coordinated phosphinous acid-catalyzed alkylidenecyclopropanation of bicyclic alkenes with terminal alkynes

Julie Bigeault; Laurent Giordano; Innocenzo de Riggi; Yves Gimbert; Gérard Buono

doi:10.1021/ol071386m

Platinum(II)-coordinated phosphinous acid-catalyzed alkylidenecyclopropanation of bicyclic alkenes with terminal alkynes

Org Lett. 2007 Aug 30;9(18):3567-70. doi: 10.1021/ol071386m. Epub 2007 Aug 1.

Authors

Julie Bigeault¹, Laurent Giordano, Innocenzo de Riggi, Yves Gimbert, Gérard Buono

Affiliation

¹ Laboratoire de Synthèse Asymétrique, UMR 6180 CNRS, Université d'Aix-Marseille P. Cézanne, Faculté des Sciences et Techniques de St Jérôme, ECM, Case A62, Avenue Escadrille Normandie Niemen, 13397 Marseille Cedex 20, France.

PMID: 17665919
DOI: 10.1021/ol071386m

Abstract

New Pt(eta2-acetato){[(R)(Ph)PO]2H} complexes 3 prepared from PtCl2(CH3CN)2 and secondary phosphine oxides (SPOs) catalyzed the [2+1] cycloaddition of phenylethyne (5a) with norbornene derivatives 4 to afford benzylidenecyclopropanes.