Period-doubling bifurcation to alternans in paced cardiac tissue: crossover from smooth to border-collision characteristics

Phys Rev Lett. 2007 Aug 3;99(5):058101. doi: 10.1103/PhysRevLett.99.058101. Epub 2007 Jul 30.

Abstract

We investigate, both experimentally and theoretically, the period-doubling bifurcation to alternans in heart tissue. Previously, this phenomenon has been modeled with either smooth or border-collision dynamics. Using a modification of existing experimental techniques, we find a hybrid behavior: Very close to the bifurcation point, the dynamics is smooth, whereas further away it is border-collision-like. The essence of this behavior is captured by a model that exhibits what we call an unfolded border-collision bifurcation. This new model elucidates that, in an experiment, where only a limited number of data points can be measured, the smooth behavior of the bifurcation can easily be missed.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Action Potentials*
  • Heart
  • Humans
  • Models, Cardiovascular*