Encephalitis in a child during atypical course of rubella

Infection. 2009 Feb;37(1):65-6. doi: 10.1007/s15010-007-6322-6. Epub 2007 Oct 31.

Abstract

Rubella is usually encountered as a mild viral illness in children and complications are not common. We reported rubella encephalitis in the atypical course of rubella without rash in a 9-year-old boy. He was admitted with a headache, fever, loss of consciousness and bilateral retroauricular lymphadenopathy. The cerebrospinal fluid (CSF) examination showed lymphocytic pleocytosis, increased protein levels and a normal glucose value. Immunoglobulin (Ig) M antibodies against rubella virus were positive in CSF and serum. IgG antibody also became positive in his serum 3 weeks after his admittance. We emphasized that rubella may appear without any rash and cause encephalitis. In unvaccinated children, rubella should be considered in the differential diagnosis of encephalitis.

Publication types

  • Case Reports

MeSH terms

  • Antibodies, Viral / blood
  • Antibodies, Viral / cerebrospinal fluid
  • Child
  • Encephalitis / pathology
  • Encephalitis / physiopathology
  • Encephalitis / virology*
  • Humans
  • Immunoglobulin G / blood
  • Immunoglobulin M / blood
  • Immunoglobulin M / cerebrospinal fluid
  • Male
  • Rubella / complications*
  • Rubella / pathology
  • Rubella / physiopathology
  • Rubella virus / immunology
  • Rubella virus / isolation & purification*

Substances

  • Antibodies, Viral
  • Immunoglobulin G
  • Immunoglobulin M