Abstract
Complex I deficiency is a frequent defect of the mitochondrial electron transport chain. We report on a 3-year-old boy, who rapidly deteriorated after sudden flushing and collapse. This fatal and unusual case was characterized by widely uncontrollable arterial hypertension. It might indicate that hypertensive crisis could be a potential manifestation of mitochondrial disorders.
MeSH terms
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Antihypertensive Agents / therapeutic use
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Blood Pressure / physiology
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Cerebral Cortex / pathology*
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Child, Preschool
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Electron Transport Complex I / deficiency*
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Humans
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Hypertensive Encephalopathy / drug therapy
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Hypertensive Encephalopathy / etiology*
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Hypertensive Encephalopathy / pathology*
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Male
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Mitochondrial Diseases / complications*
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Mitochondrial Diseases / enzymology
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Mitochondrial Diseases / pathology
Substances
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Antihypertensive Agents
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Electron Transport Complex I