Background: Ocular involvement is considered to be less frequent in Churg-Strauss syndrome than in other vasculitides.
Case: We describe the case of a patient who presented with monocular blindness due to central retinal artery occlusion, as the first symptom of Churg-Strauss syndrome.
Discussion: Acute loss of vision in a patient with hypereosinophilia should suggest Churg-Strauss syndrome, among other diagnoses. Rapid and appropriate treatment to prevent the extension of the vasculitic process is essential.