Imaging obesity: fMRI, food reward, and feeding

Cell Metab. 2007 Dec;6(6):423-5. doi: 10.1016/j.cmet.2007.11.007.

Abstract

Animal studies have revealed brain regions that control homeostatic feeding, but the rampant overeating contributing to the obesity epidemic suggests the participation of "nonhomeostatic" control centers. Recent papers by Batterham et al. (2007) and Farooqi et al. (2007) link peptide YY(3-36) and leptin to the activation of nonhomeostatic brain regions.

Publication types

  • Comment

MeSH terms

  • Animals
  • Brain / physiology
  • Eating / physiology
  • Food
  • Homeostasis
  • Humans
  • Leptin / physiology
  • Magnetic Resonance Imaging
  • Models, Neurological
  • Obesity / physiopathology*
  • Obesity / psychology
  • Peptide Fragments
  • Peptide YY / physiology
  • Reward

Substances

  • Leptin
  • Peptide Fragments
  • Peptide YY
  • peptide YY (3-36)