Not just because it is there: aminoacyl-tRNA synthetases gain control of the cell

Mol Cell. 2008 Apr 11;30(1):3-4. doi: 10.1016/j.molcel.2008.03.006.

Abstract

In a recent issue of Molecular Cell, Jia et al. (2008) demonstrate that time-controlled repression of interferon-induced transcripts depends upon the interaction between an RNA structure in these transcripts and protein domains harbored by a mammalian aminoacyl-tRNA synthetase.

Publication types

  • Comment

MeSH terms

  • Amino Acyl-tRNA Synthetases / chemistry
  • Amino Acyl-tRNA Synthetases / metabolism*
  • Animals
  • Interferon-gamma / metabolism
  • Nucleic Acid Conformation
  • Protein Structure, Tertiary
  • RNA* / chemistry
  • RNA* / metabolism

Substances

  • RNA
  • Interferon-gamma
  • Amino Acyl-tRNA Synthetases